Keep track of Intently (one)pentobarbital will reduce the extent or impact of fentanyl by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to your reduce in fentanyl plasma concentrations, insufficient efficacy or, perhaps, progress of the with